A team has finished a game with 4-21-1 runs-hits-errors line 1 time since 1897, most recently Baltimore Orioles on 5 September 2003. That is about one every 443,004 team-games.
Box score for the most recent one ↗
4-18-4 4-19-1 4-19-3 4-19-0 4-19-2 4-20-1 4-21-1 4-22-0 4-24-4 5-1-0 5-1-1 5-2-0 5-2-1
The whole distribution — Runs-Hits-Errors Lines · All 18 shapes