45-21 in NFL history
7 completed games with this score pair in the covered 7,355 games. Scores list the higher score first, regardless of home or away.
| Date | Matchup | Result |
|---|---|---|
| 2026-10-11 | DET at ARI | 45–21 |
| 2025-12-21 | CIN at MIA | 45–21 |
| 2017-11-13 | MIA at CAR | 21–45 |
| 2014-11-30 | TEN at HOU | 21–45 |
| 2014-11-10 | CAR at PHI | 21–45 |
| 2013-10-27 | WAS at DEN | 21–45 |
| 2006-11-26 | PHI at IND | 21–45 |
Sources and coverage
Derived from nflverse data. Player and schedule histories start in 1999; drive and play findings currently cover the 2026 season. Updated 2026-10-15. Recent results can change after official scoring corrections. Source terms and attribution.