There have been 101 four-strikeout innings since 1988, measured across 93,554 games — one every 926 games. The most recent was Mason Miller on 9 May 2026; the first was Charlie Hough on 4 July 1988.
| Date | Player | # | Game | |
|---|---|---|---|---|
| 2026-05-09 | Mason Miller | 4 | 101 | ↗ |
| 2026-04-25 | Jake Irvin | 4 | 100 | ↗ |
| 2026-03-27 | Jeff Hoffman | 4 | 99 | ↗ |
| 2025-09-07 | Aroldis Chapman | 4 | 98 | ↗ |
| 2025-06-19 | Steven Matz | 4 | 97 | ↗ |
| 2024-09-17 | Luis Frias | 4 | 96 | ↗ |
| 2023-07-21 | Jose Hernandez | 4 | 95 | ↗ |
| 2023-07-07 | Tyler Glasnow | 4 | 94 | ↗ |
| 2023-04-30 | Brady Singer | 4 | 93 | ↗ |
| 2022-08-17 | Andrew Chafin | 4 | 92 | ↗ |
| 2022-08-15 | Chris Martin | 4 | 91 | ↗ |
| 2022-04-30 | Michael Rucker | 4 | 90 | ↗ |
| 2021-09-24 | Craig Stammen | 4 | 89 | ↗ |
| 2021-08-24 | Andrew Wantz | 4 | 88 | ↗ |
| 2021-07-25 | Domingo German | 4 | 87 | ↗ |
| 2021-06-25 | Jonathan Loaisiga | 4 | 86 | ↗ |
| 2021-06-11 | Clayton Kershaw | 4 | 85 | ↗ |
| 2021-05-22 | Lance McCullers | 4 | 84 | ↗ |
| 2021-04-23 | Tyler Glasnow | 4 | 83 | ↗ |
| 2019-09-27 | Buddy Boshers | 4 | 82 | ↗ |
| 2019-08-31 | Buck Farmer | 4 | 81 | ↗ |
| 2019-04-22 | Luke Bard | 4 | 80 | ↗ |
| 2018-07-26 | Zack Godley | 4 | 79 | ↗ |
| 2018-07-08 | Miguel Diaz | 4 | 78 | ↗ |
| 2018-05-08 | Blake Snell | 4 | 77 | ↗ |
| 2018-04-17 | Ryan Dull | 4 | 76 | ↗ |
| 2018-03-29 | Zach Duke | 4 | 75 | ↗ |
| 2017-08-13 | Zack Godley | 4 | 74 | ↗ |
| 2017-07-18 | Mike Bolsinger | 4 | 73 | ↗ |
| 2017-05-25 | Craig Kimbrel | 4 | 72 | ↗ |
| 2017-05-03 | Nathan Karns | 4 | 71 | ↗ |
| 2017-04-23 | Michael Tonkin | 4 | 70 | ↗ |
| 2017-04-20 | Clayton Richard | 4 | 69 | ↗ |
| 2016-09-17 | Jon Gray | 4 | 68 | ↗ |
| 2016-09-06 | James Paxton | 4 | 67 | ↗ |
| 2016-08-12 | Jake Thompson | 4 | 66 | ↗ |
| 2016-08-07 | Ken Giles | 4 | 65 | ↗ |
| 2016-05-24 | Julio Teheran | 4 | 64 | ↗ |
| 2016-05-08 | Tyler Duffey | 4 | 63 | ↗ |
| 2016-04-17 | Jerry Blevins | 4 | 62 | ↗ |
| 2015-10-04 | Will Smith | 4 | 61 | ↗ |
| 2015-05-16 | Sergio Santos | 4 | 60 | ↗ |
| 2015-05-15 | Kenley Jansen | 4 | 59 | ↗ |
| 2014-09-20 | Oliver Perez | 4 | 58 | ↗ |
| 2014-08-29 | Justin Grimm | 4 | 57 | ↗ |
| 2014-07-25 | Zack Greinke | 4 | 56 | ↗ |
| 2014-07-19 | Brett Cecil | 4 | 55 | ↗ |
| 2013-05-10 | Alex Cobb | 4 | 54 | ↗ |
| 2013-04-28 | Tony Cingrani | 4 | 53 | ↗ |
| 2012-09-26 | Craig Kimbrel | 4 | 52 | ↗ |
| 2012-09-25 | Zack Greinke | 4 | 51 | ↗ |
| 2012-09-20 | Jason Berken | 4 | 50 | ↗ |
| 2012-09-20 | Phil Hughes | 4 | 49 | ↗ |
| 2012-08-13 | Steve Delabar | 4 | 48 | ↗ |
| 2012-06-05 | Francisco Liriano | 4 | 47 | ↗ |
| 2012-04-27 | Ryan Cook | 4 | 46 | ↗ |
| 2012-04-24 | Bud Norris | 4 | 45 | ↗ |
| 2011-09-17 | Yovani Gallardo | 4 | 44 | ↗ |
| 2011-08-25 | Jeremy Hellickson | 4 | 43 | ↗ |
| 2011-08-04 | Justin Masterson | 4 | 42 | ↗ |
| 2011-06-24 | A.J. Burnett | 4 | 41 | ↗ |
| 2010-06-06 | Manny Parra | 4 | 40 | ↗ |
| 2010-06-03 | Felix Hernandez | 4 | 39 | ↗ |
| 2009-10-04 | Ryan Dempster | 4 | 38 | ↗ |
| 2009-10-04 | Luke Gregerson | 4 | 37 | ↗ |
| 2008-06-21 | Joe Saunders | 4 | 36 | ↗ |
| 2008-06-15 | Scott Baker | 4 | 35 | ↗ |
| 2006-09-23 | Brad Penny | 4 | 34 | ↗ |
| 2006-04-26 | Jon Rauch | 4 | 33 | ↗ |
| 2004-08-03 | Mike Stanton | 4 | 32 | ↗ |
| 2004-06-13 | Brad Lidge | 4 | 31 | ↗ |
| 2003-06-11 | Octavio Dotel | 4 | 30 | ↗ |
| 2003-05-22 | Darren Dreifort | 4 | 29 | ↗ |
| 2003-04-04 | Arthur Rhodes | 4 | 28 | ↗ |
| 2002-09-02 | Kerry Wood | 4 | 27 | ↗ |
| 2002-07-05 | A.J. Burnett | 4 | 26 | ↗ |
| 2001-07-22 | Frankie Rodriguez | 4 | 25 | ↗ |
| 2001-06-30 | Erik Hiljus | 4 | 24 | ↗ |
| 2000-05-05 | Ugueth Urbina | 4 | 23 | ↗ |
| 2000-04-16 | Chuck Finley | 4 | 22 | ↗ |
| 1999-08-17 | Steve Kline | 4 | 21 | ↗ |
| 1999-08-15 | Chuck Finley | 4 | 20 | ↗ |
| 1999-08-10 | Tim Wakefield | 4 | 19 | ↗ |
| 1999-07-22 | Jerry Spradlin | 4 | 18 | ↗ |
| 1999-05-12 | Chuck Finley | 4 | 17 | ↗ |
| 1999-04-28 | Archie Corbin | 4 | 16 | ↗ |
| 1998-09-16 | Kirt Ojala | 4 | 15 | ↗ |
| 1998-07-27 | Blake Stein | 4 | 14 | ↗ |
| 1997-07-21 | Wilson Alvarez | 4 | 13 | ↗ |
| 1996-09-13 | Derek Wallace | 4 | 12 | ↗ |
| 1996-09-03 | Kevin Appier | 4 | 11 | ↗ |
| 1996-07-25 | Bruce Ruffin | 4 | 10 | ↗ |
| 1995-09-19 | Darren Holmes | 4 | 9 | ↗ |
| 1995-06-07 | Mark Wohlers | 4 | 8 | ↗ |
| 1994-05-14 | Paul Shuey | 4 | 7 | ↗ |
| 1994-04-11 | Eric Plunk | 4 | 6 | ↗ |
| 1990-09-09 | Matt Young | 4 | 5 | ↗ |
| 1990-06-04 | Tim Birtsas | 4 | 4 | ↗ |
| 1989-08-22 | Derek Lilliquist | 4 | 3 | ↗ |
| 1988-08-13 | Jeff Robinson | 4 | 2 | ↗ |
| 1988-07-04 | Charlie Hough | 4 | 1 | ↗ |